Sofinnova Investments, Inc.

CIK 1631134 · EDGAR ↗
sum of disclosed values for 2026-03-31; 0 positions have no disclosed value and are left out of the sum, counted here rather than dropped
$2.6B
every reported holding for this filer and quarter, including ones with no disclosed value
75
positions with no comparable holding in the prior quarter (kind new), 2026-03-31
30
positions absent from this quarter's filing after being held last quarter (kind exit), 2026-03-31 — inferred from absence, not a sale record
16
Quarter-end snapshot, filed up to 45 days later — not current holdings. What a 13F covers ↓
FILING WINDOW OPEN
Q3 2026 filings are due by 2026-11-16 — figures for that quarter will change; missing filers are not zeros.

Changes · Quarter ended 2026-03-31. Newest filing in this build: 2026-07-31. Per-row filing dates are on each receipt.

by shares · How classified ↗
Period
Position changes into quarter 2026-03-31
The reviewed ticker for the filed issuer name and share class, the same mapping the Reported positions table uses. Symbols are never inferred from names; — means no reviewed mapping.position matched across quarters by exact reported CUSIP over a registry gap — never a name matchNEW / ADD / TRIM / EXIT by share count · NO CHANGE = same shares; the value moved with price, so never an ADD or a TRIM · EXIT = absent this quarter (disposed, delisted, confidential, or reported by an affiliate) — the filing does not say which · NO PRIOR = no comparable prior quarter on record (a first filing, or a quarter filed inside an affiliate's report), so not called a new stake · n/c = not classifiable: value undisclosed on one side of the pair, or neither shares nor value can classify it · †v: the reported share count is unchanged across the pair; this build's data classified the change from its reported value; builds from 2026-09-10 on read it as NO CHANGEderived by Public Filings from the published data; “no value” means the source did not disclose a usable value — never zeroreported unit changed across the pair (SH↔PRN); the share delta is withheld rather than fabricatedPrev valueCurr valuePrev sharesCurr shares
—share class as filed: RUSSELL 2000 ETF · position key pos:15702 · issuer key iss:1012 PUTNEW+$149M+600,000$0$149M—600,000
—share class as filed: STATE STREET SPD · position key pos:10141 · issuer key iss:1602 PUTNEW+$134M+1,050,000$0$134M—1,050,000
a reviewed mapping row for this filed issuer name and share class (never inferred from the name)share class as filed: COM · position key pos:15008 · issuer key iss:318ADD+$39.0M+475,727$81.6M$121M1,512,9941,988,721
a reviewed mapping row for this filed issuer name and share class (never inferred from the name)share class as filed: SHS USD · position key pos:14655 · issuer key iss:2143TRIM−$50.1M−361,533$163M$113M959,860598,327
a reviewed mapping row for this filed issuer name and share class (never inferred from the name)share class as filed: COM · position key pos:15016 · issuer key iss:1868ADD+$18.1M+2,429$76.8M$94.9M157,641160,070
a reviewed mapping row for this filed issuer name and share class (never inferred from the name)share class as filed: ORD · position key pos:17695 · issuer key iss:2037NEW+$89.9M+456,031$0$89.9M—456,031
a reviewed mapping row for this filed issuer name and share class (never inferred from the name)share class as filed: UNIT SER 1 · position key pos:11173 · issuer key iss:995 PUTNEW+$86.6M+150,000$0$86.6M—150,000
a reviewed mapping row for this filed issuer name and share class (never inferred from the name)share class as filed: COM · position key pos:17421 · issuer key iss:475ADD+$11.2M+139,926$70.1M$81.4M1,973,6252,113,551
—share class as filed: ISHARES BIOTECH · position key pos:13874 · issuer key iss:1012 PUTNEW+$80.2M+475,000$0$80.2M—475,000
—share class as filed: COM · position key pos:15677 · issuer key iss:1851ADD+$64.0M+3,062,588$1.9M$65.9M83,3003,145,888
a reviewed mapping row for this filed issuer name and share class (never inferred from the name)share class as filed: COM PAR $.01 · position key pos:14207 · issuer key iss:973ADD+$29.3M+189,274$27.3M$56.6M156,801346,075
a reviewed mapping row for this filed issuer name and share class (never inferred from the name)share class as filed: ORD SHS · position key pos:17782 · issuer key iss:2255ADD+$28.8M+397,452$26.2M$55.0M332,520729,972
—share class as filed: COM · position key sid:sec:prov:38b7ce53f517b4f397d48b58dc3386d9 · issuer key cusip6:868459ADD+$21.8M+401,214$27.5M$49.3M553,095954,309
a reviewed mapping row for this filed issuer name and share class (never inferred from the name)share class as filed: COM · position key pos:15016 · issuer key iss:1868 PUTNEW+$47.6M+80,300$0$47.6M—80,300
a reviewed mapping row for this filed issuer name and share class (never inferred from the name)share class as filed: COM · position key pos:11035 · issuer key iss:266ADD+$2.7M+84,849$41.4M$44.2M697,133781,982
a reviewed mapping row for this filed issuer name and share class (never inferred from the name)share class as filed: COM · position key pos:11450 · issuer key iss:267NEW+$42.1M+229,521$0$42.1M—229,521
a reviewed mapping row for this filed issuer name and share class (never inferred from the name)share class as filed: COM · position key pos:10390 · issuer key iss:416ADD+$11.9M+66,758$29.9M$41.8M299,417366,175
a reviewed mapping row for this filed issuer name and share class (never inferred from the name)share class as filed: COM · position key pos:16702 · issuer key iss:1556ADD+$10.1M+178,702$29.1M$39.1M271,394450,096
—share class as filed: COM · position key sid:sec:prov:f7d48a640772d3aa60939ca4949078c5 · issuer key cusip6:45166AADD+$7.1M+246,665$30.6M$37.7M885,1211,131,786
a reviewed mapping row for this filed issuer name and share class (never inferred from the name)share class as filed: COM · position key pos:14355 · issuer key iss:957ADD+$2.5M+83,427$34.8M$37.2M1,618,4771,701,904

Flags: no row carries a flag.

1–20 of the 81 changes on this page

Mark-to-market only (no share change) · 9

Positions whose share count is identical in both quarters; the value changed with price, not with a decision.

Positions held with no share change into quarter 2026-03-31
The reviewed ticker for the filed issuer name and share class, the same mapping the Reported positions table uses. Symbols are never inferred from names; — means no reviewed mapping.position matched across quarters by exact reported CUSIP over a registry gap — never a name matchNEW / ADD / TRIM / EXIT by share count · NO CHANGE = same shares; the value moved with price, so never an ADD or a TRIM · EXIT = absent this quarter (disposed, delisted, confidential, or reported by an affiliate) — the filing does not say which · NO PRIOR = no comparable prior quarter on record (a first filing, or a quarter filed inside an affiliate's report), so not called a new stake · n/c = not classifiable: value undisclosed on one side of the pair, or neither shares nor value can classify it · †v: the reported share count is unchanged across the pair; this build's data classified the change from its reported value; builds from 2026-09-10 on read it as NO CHANGEderived by Public Filings from the published data; “no value” means the source did not disclose a usable value — never zeroreported unit changed across the pair (SH↔PRN); the share delta is withheld rather than fabricatedPrev valueCurr valuePrev sharesCurr shares
a reviewed mapping row for this filed issuer name and share class (never inferred from the name)share class as filed: COM · position key pos:13186 · issuer key iss:1273NO CHANGE−$45.1M0$355M$310M1,550,2801,550,280
—share class as filed: CL A · position key sid:sec:prov:c6f0567aff349dfe2dab4a6ee5ba8988 · issuer key cusip6:92337RNO CHANGE−$29.1M0$141M$112M2,793,9872,793,987
—share class as filed: COM · position key sid:sec:prov:9fd554b76cc510ac236cd887d1f06195 · issuer key cusip6:75383LNO CHANGE+$1.8M0$57.8M$59.6M1,904,4081,904,408
—share class as filed: COM · position key sid:sec:prov:09a6575686667c84597e4fe2b4841977 · issuer key cusip6:09077VNO CHANGE+$9.8M0$30.3M$40.1M2,293,7882,293,788
—share class as filed: COM · position key sid:sec:prov:1a78f2f31f5e82c1522796ab4aa69fd1 · issuer key cusip6:04272NNO CHANGE+$5.0M0$34.1M$39.1M1,696,7521,696,752
—share class as filed: COM · position key sid:sec:prov:60b0d2b7a0a89427b98ad9e1fd59d494 · issuer key cusip6:65343ENO CHANGE−$782K0$3.2M$2.4M222,654222,654
—share class as filed: COM · position key sid:sec:prov:3b4a08cf659449a1ac1d2ee41e501b50 · issuer key cusip6:008064NO CHANGE−$148K0$1.7M$1.5M107,391107,391
—share class as filed: COM · position key sid:sec:prov:4e1251cac1f489d2ab1b0a155436af89 · issuer key cusip6:097702NO CHANGE−$197K0$753K$556K137,721137,721
—share class as filed: COM · position key sid:sec:prov:6db6b47119928ad4af3cf49015c9c5eb · issuer key cusip6:45175GNO CHANGE−$60.6K0$220K$159K31,88431,884

Flags: no row carries a flag.

Holdings without a security ID are counted, not compared. Method ↗

Reported positions — 2026-03-31

68 issuers · 75 rows
View
This build carries one quarter for this manager: 2026-03-31. Notable managers carry four published quarters, others two.
Positions Sofinnova Investments, Inc. reported for the quarter ended 2026-03-31, as that filer reported them
This list carries reported issuer names and security identities, without a dated ticker mapping. Symbols are not inferred from names.a position composed from a base filing plus NEW-HOLDINGS amendments keeps every source row here; the composition's latest filed date is the one shown served from this build's published holdings (derived from the filer's own reported rows); every row resolves to its filingShare of total reported value, calculated only when the full position list has disclosed values. This is 13F long value, not total assets.value undisclosed on the filing: retained and counted, excluded from sums, never shown as $0SharesWt
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Natera Inc · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$310M1,550,28011.8%
—iShares TR
2 positions · 2 reported rows
Rows Sofinnova Investments, Inc. reported for iShares TR, as it reported them
iShares TR · RUSSELL 2000 ETF · PUT CUSIP — $149M600,000
iShares TR · ISHARES BIOTECH · PUT CUSIP — $80.2M475,000
ticker not yet mapped
$229M1,075,0008.7%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)United Therapeutics Corp
2 positions · 2 reported rows
Rows Sofinnova Investments, Inc. reported for United Therapeutics Corp, as it reported them
United Therapeutics Corp · COM CUSIP — $94.9M160,070
United Therapeutics Corp · COM · PUT CUSIP — $47.6M80,300
$143M240,3705.4%
—SPDR Series Trust · STATE STREET SPD · PUT CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
ticker not yet mapped
$134M1,050,0005.1%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Bristol-Myers Squibb Co · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$121M1,988,7214.6%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Jazz Pharmaceuticals PLC · SHS USD CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$113M598,3274.3%
—Vera Therapeutics Inc · CL A CUSIP 92337R101
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
ticker not yet mapped
$112M2,793,9874.3%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)AstraZeneca PLC · ORD CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$89.9M456,0313.4%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Invesco QQQ TR · UNIT SER 1 · PUT CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$86.6M150,0003.3%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Cogent Biosciences Inc · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$81.4M2,113,5513.1%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Celcuity Inc
2 positions · 2 reported rows
Rows Sofinnova Investments, Inc. reported for Celcuity Inc, as it reported them
Celcuity Inc · COM CUSIP — $41.8M366,175
Celcuity Inc · COM · PUT CUSIP — $34.2M300,000
$76.0M666,1752.9%
—Ultragenyx Pharmaceutical Inc
2 positions · 2 reported rows
Rows Sofinnova Investments, Inc. reported for Ultragenyx Pharmaceutical Inc, as it reported them
Ultragenyx Pharmaceutical Inc · COM CUSIP — $65.9M3,145,888
Ultragenyx Pharmaceutical Inc · COM · CALL CUSIP — $7.3M350,000
ticker not yet mapped
$73.2M3,495,8882.8%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Axsome Therapeutics Inc.
2 positions · 2 reported rows
Rows Sofinnova Investments, Inc. reported for Axsome Therapeutics Inc., as it reported them
Axsome Therapeutics Inc. · COM CUSIP — $36.0M212,747
Axsome Therapeutics Inc. · COM · PUT CUSIP — $33.8M200,000
$69.8M412,7472.7%
—Rapport Therapeutics Inc · COM CUSIP 75383L102
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
ticker not yet mapped
$59.6M1,904,4082.3%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Insmed Inc · COM PAR $.01 CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$56.6M346,0752.2%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Alcon AG · ORD SHS CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$55.0M729,9722.1%
—Supernus Pharmaceuticals · COM CUSIP 868459108
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
ticker not yet mapped
$49.3M954,3091.9%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)BioMarin Pharmaceutical Inc · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$44.2M781,9821.7%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Biogen Inc · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$42.1M229,5211.6%
—BioAge Labs Inc · COM CUSIP 09077V100
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
ticker not yet mapped
$40.1M2,293,7881.5%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Rhythm Pharmaceuticals Inc · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$39.1M450,0961.5%
—Arrivent BioPharma Inc · COM CUSIP 04272N102
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
ticker not yet mapped
$39.1M1,696,7521.5%
—IDEAYA Biosciences Inc · COM CUSIP 45166A102
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
ticker not yet mapped
$37.7M1,131,7861.4%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Immunome Inc · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$37.2M1,701,9041.4%
—Nektar Therapeutics · COM CUSIP 640268306
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
ticker not yet mapped
$36.7M509,5461.4%
—Immatics N.V · SHS CUSIP N44445109
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
ticker not yet mapped
$35.7M3,630,4541.4%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)BridgeBio Pharma Inc · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$30.4M409,1831.2%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Dyne Therapeutics Inc · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$29.6M1,633,8971.1%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Inhibrx Biosciences Inc · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$27.3M406,0291.0%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Dexcom Inc · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$24.7M393,5760.9%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Pharvaris N V · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$23.1M818,3280.9%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Pfizer Inc · COM · CALL CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$22.5M800,0000.9%
—Praxis Precision Medicines Inc · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
ticker not yet mapped
$20.5M63,6800.8%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Genmab A/S · SPONSORED ADS CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$20.2M752,2610.8%
—Arcus Biosciences Inc · COM CUSIP 03969F109
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
ticker not yet mapped
$19.9M923,0860.8%
—Liquidia Corporation · COM · PUT CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
ticker not yet mapped
$18.9M500,0000.7%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Xenon Pharmaceuticals Inc · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$17.7M305,2160.7%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Stryker Corporation · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$14.6M44,4800.6%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)AnaptysBio Inc · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$13.8M248,2530.5%
—Compass Therapeutics Inc
2 positions · 2 reported rows
Rows Sofinnova Investments, Inc. reported for Compass Therapeutics Inc, as it reported them
Compass Therapeutics Inc · COM CUSIP 20454B104 $10.9M2,056,161
Compass Therapeutics Inc · COM · CALL CUSIP 20454B104 $2.6M500,000
ticker not yet mapped
$13.5M2,556,1610.5%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Roivant Sciences Ltd · SHS CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$13.2M477,9950.5%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Edgewise Therapeutics Inc · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$12.2M386,4980.5%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Exelixis Inc · COM · PUT CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$10.8M251,5000.4%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Oric Pharmaceuticals Inc · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$8.6M679,5780.3%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Tango Therapeutics Inc · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$8.3M395,0810.3%
—Tyra Biosciences Inc · COM CUSIP 90240B106
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
ticker not yet mapped
$7.8M204,0150.3%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Replimune Group Inc
1 position · 2 reported rows
Rows Sofinnova Investments, Inc. reported for Replimune Group Inc, as it reported them
Replimune Group Inc · COM · CALL CUSIP — $3.9M512,300
Replimune Group Inc · COM · CALL CUSIP — $3.8M503,100
$7.8M1,015,4000.3%
—AxoGen Inc · COM CUSIP 05463X106
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
ticker not yet mapped
$7.0M210,6650.3%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Definium Therapeutics Inc · COM SHS CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$6.5M344,1660.2%
—Cytokinetics Inc · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
ticker not yet mapped
$6.0M91,7910.2%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Disc Medicine Inc · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$5.0M78,3200.2%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Veradermics Inc · COMMON STOCK CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$4.6M73,3150.2%
—Harmony Biosciences Hldgs Inc · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
ticker not yet mapped
$4.3M152,6950.2%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Vaxcyte Inc · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$2.9M50,6000.1%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Mirum Pharmaceuticals Inc · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$2.5M27,5910.1%
—Nextcure Inc · COM CUSIP 65343E207
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
ticker not yet mapped
$2.4M222,6540.1%
—Savara Inc · COM CUSIP 805111101
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
ticker not yet mapped
$2.0M364,7630.1%
—Establishment Labs Hldgs Inc · COM CUSIP G31249108
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
ticker not yet mapped
$1.9M33,9300.1%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Acadia Pharmaceuticals Inc · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$1.7M78,5510.1%
—Tenax Therapeutics Inc · COM CUSIP 88032L605
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
ticker not yet mapped
$1.7M104,4000.1%
—Jade Biosciences Inc · COM CUSIP 008064206
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
ticker not yet mapped
$1.5M107,3910.1%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)Wave Life Sciences Ltd · SHS CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$1.4M189,2530.1%
—Septerna Inc · COM CUSIP 81734D104
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
ticker not yet mapped
$1.1M47,5060.0%
—Onkure Therapeutics Inc · COM CL A CUSIP 68277Q105
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
ticker not yet mapped
$587K141,7000.0%
—Bolt Biotherapeutics Inc · COM CUSIP 097702203
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
ticker not yet mapped
$556K137,7210.0%
—Soleno Therapeutics Inc · COM CUSIP 834203309
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
ticker not yet mapped
$492K14,6890.0%
—ImageneBio Inc · COM CUSIP 45175G207
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
ticker not yet mapped
$159K31,8840.0%
—Zymeworks Inc · COM CUSIP 98985Y108
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
ticker not yet mapped
$40.3K1,6100.0%

1–20 of 68 issuers

1–68 of 68 issuers · page 1 of 1
One line per issuer, largest first — open a line for its reported rows. Grouping ↗

Book shape

Tick = median of the 8,748 tracked filers with a 2026-03-31 book (the index median: the 8,662 with a complete book). Concentration uses reported 13F long value, not total assets; the index is withheld when any position lacks a value.
share of the period's disclosed value held in the top-N positions; denominator is reported 13F value, not total assets
77.0%below median 80.0%
integer Herfindahl–Hirschman index in basis points over disclosed position values
374 bpsbelow median 446 bps
holdings with no disclosed value (undisclosed, or unreadable on the filing) — kept and counted, never shown as zero
75 / 75median book 97.5 positions

90 quarter-over-quarter rows

Filing history

Available filing periods
PeriodSource
2026-03-31EDGAR ↗
Complete source filings on SEC EDGAR

The filing on EDGAR is the record, including any filed after this build.

Open Sofinnova Investments, Inc.'s 13F filings on SEC EDGAR ↗
A 13F is a quarterly, long-only snapshot filed up to 45 days late — not current holdings. what a 13F covers ↗

13F reports cover LONG positions in Section 13(f) securities (US exchange-traded equities plus reportable options, warrants, certain convertibles) held by managers with at least $100M in such securities — so managers below that threshold are absent entirely. No short positions, no cash, no non-13(f) assets — not a full portfolio, and not a census of institutional ownership.

Positions are quarter-end snapshots filed up to 45 days late — not current holdings: a position may have changed or closed since the quarter ended.

Values are the manager's stated market value at quarter-end in era-dependent units (whole dollars for form versions effective 2023-01-03 onward, thousands before), normalized here to whole dollars; each record notes its original unit.

Affiliated managers may report the same position, so one position can appear under more than one filer.

Positions under confidential treatment may be omitted until a later amendment discloses them.

These are disclosures, not investment advice.