RTW INVESTMENTS, LP

$10.0B reported 13(f) long value · latest quarter 2026-03-31 · CIK 0001493215 · EDGAR ↗
A quarter-end snapshot. Filed up to 45 days later, so this page is not current holdings and never a complete portfolio. what a 13F is — and is not ↓ · methodology §13F ↗
Period
$10.0B
reported valuesum of disclosed values for 2026-03-31; 0 positions carry a NULL value and are excluded from the sum, surfaced here rather than folded away
88
positionsALL retained default holdings for this (filer, period), including NULL-value ones
9
new stakespositions with no comparable holding in the prior quarter (kind new), 2026-03-31
12
exitspositions absent from this quarter's filing after being held last quarter (kind exit), 2026-03-31 — inferred from absence, not a sale record

Position changes — into 2026-03-31

by shares · Δ value · filing link · how changes are classified §
Position changes into quarter 2026-03-31
Positionposition matched across quarters by exact reported CUSIP over a registry gap — producer-reconciled identity, never a name match identity_reconciled_by_cusipChangethe reported share count is unchanged across the pair, so the position reads as held rather than as a buy or a sell; only builds before this release inferred a direction from the reported value instead classified_by_value · "exit" = absent this quarter: disposed, delisted, under confidential treatment, or reported instead by an affiliated manager — the filing does not say which · change not classifiable: value undisclosed on one side of the quarter pair, or neither shares nor value can classify it · "no change" = the share count is identical in both quarters; the value moved only with price, so the row is mark-to-market and never an add or a trim (Add / New / Trim / Exit / No change) · "no prior" = this filer has no comparable holdings list for the previous quarter on record — a first filing under this registration, or a quarter reported inside an affiliated manager's filing — so the position is not called a new stakeΔ valuederived by Public Filings from the published aggregate; NULL means the source did not disclose a usable value — never zeroΔ sharesreported unit changed across the pair (SH↔PRN); the share delta is withheld rather than fabricated shares_unit_mismatchPrev valueCurr valuePrev sharesCurr sharesFlags
INSMED INC COM PAR $.01position key pos:15087 · issuer key iss:1181add−$50.9M+1$843M$792M4,842,8794,842,880
ARGENX SE SPONSORED ADRposition key pos:18170 · issuer key iss:242add−$48.3M+35,949$566M$518M673,497709,446
CG ONCOLOGY INC COMposition key pos:12402 · issuer key iss:558add+$389M+4,972,681$83.5M$473M2,012,1276,984,808
CELCUITY INC COMposition key pos:11232 · issuer key iss:542add+$292M+2,489,461$54.9M$347M550,1603,039,621
TANGO THERAPEUTICS INC COMposition key pos:12388 · issuer key iss:2086add+$265M+11,809,392$13.2M$278M1,491,22813,300,620
ERASCA INC COMposition key pos:12600 · issuer key iss:846add+$261M+16,010,524$546K$261M146,65116,157,175
NATERA INC COMposition key pos:14059 · issuer key iss:1529trim−$93.6M−250,000$344M$250M1,500,0001,250,000
RADNET INC COMposition key pos:11987 · issuer key iss:1799add−$41.5M+346,500$281M$239M3,938,5004,285,000
TARSUS PHARMACEUTICALS INC COMposition key pos:11454 · issuer key iss:2092add−$38.4M+10,705$273M$235M3,335,3203,346,025
APOGEE THERAPEUTICS INC COMposition key pos:14112 · issuer key iss:217add+$29.5M+70,000$205M$234M2,712,0972,782,097
COGENT BIOSCIENCES INC COMposition key pos:18333 · issuer key iss:610trim−$59.6M−2,133,566$270M$210M7,592,2415,458,675
IRHYTHM HOLDINGS INC COMposition key pos:13207 · issuer key iss:1153add−$12.8M+486,510$210M$197M1,181,9901,668,500
STOKE THERAPEUTICS INC COMposition key sid:sec:prov:3fee4169345e05a49cf14bcc2babfc71 · issuer key cusip6:86150Radd+$7.0M+76,669$176M$183M5,546,8565,623,525
ESTABLISHMENT LABS HLDGS INC COMposition key sid:sec:prov:7bf59fd7aeffb1ecf2ffdacd97c7e39d · issuer key cusip6:G31249add−$37.9M+66,864$189M$151M2,588,8312,655,695
APELLIS PHARMACEUTICALS INC COMposition key sid:sec:prov:233302be8852a126d4f3dc726082a4c4 · issuer key cusip6:03753Utrim−$44.3M−3,981,719$193M$148M7,666,7643,685,045
REPLIGEN CORP COMposition key pos:13464 · issuer key iss:1834add−$32.3M+142,000$174M$142M1,064,0001,206,000
IMMATICS N.V SHSposition key sid:sec:prov:8771e17f16590b5bd511978f2a4f7807 · issuer key cusip6:N44445add+$6.6M+1,435,986$120M$127M11,433,35412,869,340
ZAI LAB LTD ADRposition key pos:14704 · issuer key cusip6:98887Qtrim+$900K−385,000$123M$124M6,959,0326,574,032
INTUITIVE SURGICAL INC COM NEWposition key pos:17712 · issuer key iss:1213add+$44.1M+118,772$57.3M$101M101,228220,000
CENTESSA PHARMACEUTICALS PLC SPONSORED ADSposition key pos:18882 · issuer key cusip6:152309add+$36.8M+263,338$44.8M$81.6M1,790,8372,054,175
IMMUNOVANT INC COMposition key sid:sec:prov:c0680e314bfe2d1131f5c3d642c67920 · issuer key cusip6:45258Jtrim−$1.8M−1$80.8M$78.9M3,177,8503,177,849
ULTRAGENYX PHARMACEUTICAL IN COMposition key pos:16570 · issuer key iss:2194add+$7.4M+648,656$69.0M$76.4M3,000,1393,648,795
HINGE HEALTH INC CL Aposition key sid:sec:prov:15b122a1959cdc720dffb69686bc9994 · issuer key cusip6:433313add+$58.0M+1,576,500$16.4M$74.4M353,5001,930,000
CASTLE BIOSCIENCES INC COMposition key sid:sec:prov:fd9590ea03898824f7f15a013603f826 · issuer key cusip6:14843Cadd−$14.6M+643,098$82.3M$67.7M2,115,2372,758,335
TAYSHA GENE THERAPIES INC COM SHSposition key pos:14669 · issuer key iss:2095trim−$29.0M−2,718,049$90.2M$61.2M16,398,29713,680,248
COMPASS PATHWAYS PLC SPONSORED ADSposition key sid:sec:prov:88f799da4526ad1ae0a440740a6e9c1b · issuer key cusip6:20451Wadd−$1.6M+1,875,000$60.4M$58.8M8,757,39010,632,390
KODIAK SCIENCES INC COMposition key sid:sec:prov:b6301632224d8122ae8dff0115962cfa · issuer key cusip6:50015Madd+$15.1M+1$41.6M$56.7M1,487,9331,487,934
REPLIMUNE GROUP INC COMposition key pos:13385 · issuer key iss:1836add−$13.1M+216,564$69.4M$56.3M7,140,3527,356,916
CRINETICS PHARMACEUTICALS IN COMposition key pos:15866 · issuer key iss:682add−$10.2M+100,000$62.9M$52.7M1,351,3261,451,326
UNIQURE NV SHSposition key pos:11923 · issuer key iss:2710trim−$46.5M−1,125,106$88.8M$42.3M3,711,4622,586,356
WAYSTAR HLDG CORP COMposition key pos:15916 · issuer key iss:2313new+$39.3M+1,630,000$0$39.3M1,630,000
ARROWHEAD PHARMACEUTICALS IN COMposition key pos:16618 · issuer key iss:249add−$2.1M+966$38.8M$36.7M584,716585,682
EVOMMUNE INC COM SHSposition key sid:sec:prov:adbff6ad799c41f5a1fe4cddc6ffc42b · issuer key cusip6:30054Yadd+$12.6M+218,564$22.0M$34.5M1,283,6711,502,235
STRYKER CORPORATION COMposition key pos:16108 · issuer key iss:2049trim−$53.3M−145,000$86.1M$32.9M245,000100,000
CANDEL THERAPEUTICS INC COMposition key sid:sec:prov:36c1cc87b96fff749fa3a87e5be52946 · issuer key cusip6:137404new+$31.5M+6,422,018$0$31.5M6,422,018
AQUESTIVE THERAPEUTICS INC COMposition key sid:sec:prov:287679ae59495e28d5c5c22eea9bb86e · issuer key cusip6:03843Eadd−$9.6M+1,176,471$40.4M$30.8M6,250,0007,426,471
AKTIS ONCOLOGY INC COMposition key pos:11057 · issuer key iss:119new+$28.5M+1,592,043$0$28.5M1,592,043
COMPASS THERAPEUTICS INC COMposition key sid:sec:prov:c5f3f37de4d48fd1b29c266e9a76eb0b · issuer key cusip6:20454Badd+$8.7M+1,686,599$13.4M$22.1M2,500,0004,186,599
DIANTHUS THERAPEUTICS INC COMposition key pos:18462 · issuer key iss:731new+$20.8M+248,063$0$20.8M248,063
FULGENT GENETICS INC COMposition key pos:14854 · issuer key iss:968add+$2.0M+583,973$18.5M$20.5M705,0271,289,000
BETA BIONICS INC COMposition key sid:sec:prov:4e7eb09ab13c64fd6730ede8dbc988b8 · issuer key cusip6:08659Btrim−$56.1M−500,000$76.2M$20.0M2,500,0002,000,000
CENTURY THERAPEUTICS INC COMposition key sid:sec:prov:310355a827423f86fff2dece8e909dcb · issuer key cusip6:15673Tnew+$19.7M+8,695,652$0$19.7M8,695,652
AVALO THERAPEUTICS INC COM NEWposition key sid:sec:prov:37b91915f07af95197894a79df85a91e · issuer key cusip6:05338Fnew+$12.8M+856,962$0$12.8M856,962
OCUGEN INC COMposition key sid:sec:prov:748132ab3b87c3f18391f70e454d8e10 · issuer key cusip6:67577Cnew+$12.1M+6,666,666$0$12.1M6,666,666
JADE BIOSCIENCES INC COM NEWposition key sid:sec:prov:3b4a08cf659449a1ac1d2ee41e501b50 · issuer key cusip6:008064trim−$14.3M−876,068$22.4M$8.1M1,449,273573,205
MILESTONE PHARMACEUTICALS IN COMposition key sid:sec:prov:22b723f52f71593881ef80163fb7daf8 · issuer key cusip6:59935Vadd+$2.5M+3,824,899$5.1M$7.5M2,506,1026,331,001
INVENTIVA SA ADSposition key sid:sec:prov:36f6260da0bf69546f0e601e6d5bafdc · issuer key cusip6:46124Uadd+$1.2M+1$6.0M$7.2M1,298,7011,298,702
ATAIBECKLEY INC COM SHSposition key pos:13477 · issuer key iss:265new+$7.1M+2,000,000$0$7.1M2,000,000
LARIMAR THERAPEUTICS INC COMposition key sid:sec:prov:853ca021ff04669801b685877f2dabbb · issuer key cusip6:517125trim−$5.2M−1,625,000$11.9M$6.8M3,125,0001,500,000
TENAX THERAPEUTICS INC COM NEWposition key sid:sec:prov:9e958f4e10d0d474cc9e75d42ea33a9a · issuer key cusip6:88032Ltrim+$1.3M−8,100$4.6M$5.9M378,346370,246
DEFINIUM THERAPEUTICS INC COM SHSposition key pos:17580 · issuer key iss:717new+$5.7M+300,000$0$5.7M300,000
EXAGEN INC COMposition key sid:sec:prov:6cea3d644720599797447228551acb50 · issuer key cusip6:30068Xtrim−$3.6M−395,231$4.8M$1.2M790,462395,231
pos:11227exit‡e−$269M−866,499$269M$0866,499
pos:13648exit‡e−$11.8M−200,000$11.8M$0200,000
pos:13938exit‡e−$162M−888,001$162M$0888,001
pos:17397exit‡e−$10.4M−46,000$10.4M$046,000
pos:18144exit‡e−$92.3M−324,600$92.3M$0324,600
sid:sec:prov:003ec1a792a63a6ca1608977e0029001exit‡e−$88.9M−683,294$88.9M$0683,294
sid:sec:prov:0983c227d7f489fadce1abda0a417532exit‡e−$55.5M−1,637,165$55.5M$01,637,165
sid:sec:prov:3044f98940a2897deb445091c04637d0exit‡e−$4.0M−300,000$4.0M$0300,000
sid:sec:prov:7cea07f55574bfdadadb6c74621338acexit‡e−$8.2M−2,000,000$8.2M$02,000,000
sid:sec:prov:862b191ccb923fc424f39385b48ce4f8exit‡e−$7.0M−100,000$7.0M$0100,000
sid:sec:prov:990effbc09610fc927e1edc54d252d9dexit‡e−$3.4M−447,607$3.4M$0447,607
sid:sec:prov:c788d5d7e7e35880122f2fe6fcd2b7b8exit‡e−$7.2M−5,891,430$7.2M$05,891,430

44 more changes below.

Mark-to-market only (no share change) · 36

Positions whose share count is identical in both quarters; the value changed with price, not with a decision.

Positions held with no share change into quarter 2026-03-31
Positionposition matched across quarters by exact reported CUSIP over a registry gap — producer-reconciled identity, never a name match identity_reconciled_by_cusipChangethe reported share count is unchanged across the pair, so the position reads as held rather than as a buy or a sell; only builds before this release inferred a direction from the reported value instead classified_by_value · "exit" = absent this quarter: disposed, delisted, under confidential treatment, or reported instead by an affiliated manager — the filing does not say which · change not classifiable: value undisclosed on one side of the quarter pair, or neither shares nor value can classify it · "no change" = the share count is identical in both quarters; the value moved only with price, so the row is mark-to-market and never an add or a trim (Add / New / Trim / Exit / No change) · "no prior" = this filer has no comparable holdings list for the previous quarter on record — a first filing under this registration, or a quarter reported inside an affiliated manager's filing — so the position is not called a new stakeΔ valuederived by Public Filings from the published aggregate; NULL means the source did not disclose a usable value — never zeroΔ sharesreported unit changed across the pair (SH↔PRN); the share delta is withheld rather than fabricated shares_unit_mismatchPrev valueCurr valuePrev sharesCurr sharesFlags
MADRIGAL PHARMACEUTICALS INC COMposition key pos:15238 · issuer key iss:1407no change−$117M0$1.2B$1.0B1,993,6871,993,687
PROTAGONIST THERAPEUTICS INC COMposition key pos:14826 · issuer key iss:1773no change+$91.4M0$442M$533M5,059,0535,059,053
PTC THERAPEUTICS INC COMposition key pos:18526 · issuer key iss:1662no change−$60.7M0$588M$528M7,746,4157,746,415
SPYRE THERAPEUTICS INC COM NEWposition key pos:14500 · issuer key iss:82no change+$73.8M0$137M$210M4,171,9964,171,996
CYTOKINETICS INC COM NEWposition key pos:13331 · issuer key iss:700no change+$6.4M0$173M$179M2,721,1582,721,158
ACADIA PHARMACEUTICALS INC COMposition key pos:18889 · issuer key iss:56no change−$31.8M0$191M$159M7,144,5247,144,524
IMMUNOCORE HLDGS PLC ADSposition key pos:16434 · issuer key iss:1166no change−$22.2M0$169M$147M4,869,7984,869,798
NEUROCRINE BIOSCIENCES INC COMposition key pos:12315 · issuer key iss:1552no change−$10.7M0$151M$140M1,062,0721,062,072
GUARDANT HEALTH INC COMposition key pos:18541 · issuer key iss:1057no change−$14.5M0$151M$137M1,481,0331,481,033
BELITE BIO INC SPONSORED ADSposition key sid:sec:prov:831c753eb8a6ce9972092ec4165601d4 · issuer key cusip6:07782Bno change−$372K0$114M$114M715,332715,332
ORUKA THERAPEUTICS INC COMposition key pos:14688 · issuer key iss:1638no change+$38.6M0$62.4M$101M2,058,1482,058,148
GH RESEARCH PLC ORDINARY SHARESposition key sid:sec:prov:592cbdfa12c811cc697874a89333d4bb · issuer key cusip6:G3855Lno change+$8.1M0$75.4M$83.4M5,933,8155,933,815
XENCOR INC COMposition key sid:sec:prov:bc17a1945987420f684d9107b41fd336 · issuer key cusip6:98401Fno change−$22.0M0$104M$81.7M6,777,4616,777,461
UROGEN PHARMA LTD COMposition key sid:sec:prov:a469da6cabfc03832e3d85a7bff09e97 · issuer key cusip6:M96088no change−$24.7M0$106M$81.7M4,543,8954,543,895
ROCKET PHARMACEUTICALS INC COMposition key sid:sec:prov:5db085c4e925ed01a4a1cbc6ba09d304 · issuer key cusip6:77313Fno change+$1.2M0$62.1M$63.3M17,687,77217,687,772
ALKERMES PLC SHSposition key pos:16418 · issuer key iss:2418no change+$12.3M0$46.8M$59.1M1,672,3561,672,356
ORCHESTRA BIOMED HLDGS INC COMposition key sid:sec:prov:9f123b52d9dfa5657af06135ef52f112 · issuer key cusip6:68572Mno change+$831K0$34.5M$35.3M8,306,0638,306,063
VERASTEM INC COM NEWposition key pos:14035 · issuer key cusip6:92337Cno change−$15.9M0$50.8M$34.9M6,576,3066,576,306
SAVARA INC COMposition key sid:sec:prov:2bc6a25d40cf07124e3a03bdecf4a4df · issuer key cusip6:805111no change−$3.4M0$35.9M$32.5M5,952,3805,952,380
NEUROGENE INC COMposition key sid:sec:prov:2436d0e4b9db5d946b26deb83a717d5e · issuer key cusip6:64135Mno change−$599K0$28.1M$27.5M1,362,4561,362,456
CULLINAN THERAPEUTICS INC COMposition key pos:13492 · issuer key iss:693no change+$6.6M0$17.7M$24.2M1,705,9601,705,960
KYMERA THERAPEUTICS INC COMposition key pos:13465 · issuer key iss:1310no change+$1.3M0$18.7M$20.0M240,000240,000
BEAM THERAPEUTICS INC COMposition key sid:sec:prov:fbdfb263adbfc86bd605b695db4205d4 · issuer key cusip6:07373Vno change−$2.2M0$15.8M$13.6M570,394570,394
HEARTFLOW INC COMposition key sid:sec:prov:5c9dafc33c07d8edc9231c0ecacc39e5 · issuer key cusip6:42238Dno change−$2.4M0$14.4M$12.0M495,000495,000
WAVE LIFE SCIENCES LTD SHSposition key pos:15162 · issuer key iss:2734no change−$13.2M0$23.0M$9.8M1,350,0001,350,000
PERCEPTIVE CAP SOLUTIONS COR CL A ORD SHSposition key pos:16802 · issuer key iss:2590no change−$1.5M0$9.7M$8.1M742,500742,500
CAPRICOR THERAPEUTICS INC COM NEWposition key sid:sec:prov:f5ab5fc62f8ffc42012ac685dc8651c0 · issuer key cusip6:14070Bno change+$385K0$7.2M$7.6M250,000250,000
KALARIS THERAPEUTICS INC COMposition key pos:12582 · issuer key cusip6:482929no change−$3.5M0$11.0M$7.5M1,300,0001,300,000
CRESCENT BIOPHARMA INC. COMposition key pos:17611 · issuer key iss:2481no change+$2.4M0$4.4M$6.8M372,856372,856
LUMEXA IMAGING HOLDINGS INC COMposition key sid:sec:prov:9e0f507ae4c750638fbe313997f8baa5 · issuer key cusip6:550249no change−$6.4M0$12.0M$5.6M650,000650,000
4D MOLECULAR THERAPEUTICS IN COMposition key sid:sec:prov:adc22e9a1524ab89aa68e69a21eb8d93 · issuer key cusip6:35104Eno change+$861K0$3.6M$4.4M475,737475,737
MEDLINE INC COM CL Aposition key pos:16301 · issuer key iss:1457no change+$175K0$2.9M$3.1M70,00070,000
OMADA HEALTH INC COMposition key sid:sec:prov:748c3ea2043f7dae881221f3c766e002 · issuer key cusip6:68170Ano change−$642K0$3.2M$2.5M200,000200,000
DISC MEDICINE INC COMposition key pos:13022 · issuer key iss:741no change−$464K0$2.4M$1.9M30,00030,000
IMAGENEBIO INC COMposition key sid:sec:prov:6db6b47119928ad4af3cf49015c9c5eb · issuer key cusip6:45175Gno change−$635K0$2.3M$1.7M334,445334,445
ROCKET PHARMACEUTICALS INC *W EXP 09/02/202position key sid:sec:prov:2e0b7c193ae04d1491f7555c4c197a31 · issuer key cusip6:77313Fno change−$1.3K0$8.5K$7.2K350,000350,000
Quarter ended 2026-03-31Newest filing in this build: 2026-07-31. Per-row filing dates are on each receipt.
Truncated by Public Filings. Changes derive from the aggregate's top-25 slices and keyable positions only; unkeyable holdings are counted in the registry, not differenced. methodology §13F ↗

Book shape

2026-03-31 · concentration · vs tracked median · tick = median
Top-25 concentration
77.0%below median 80.0%
Concentration index
372 bpsbelow median 446 bps
Positions with value
88 / 88median book 97.5 positions

Concentration uses reported 13F long value, not total assets. The index is withheld when any position lacks a value. Medians are over the 8,748 tracked filers with a 2026-03-31 book; the index median over the 8,662 with a complete book.

null-value positions: 0holdings whose <value> did not parse — retained and counted, never zero-filled · top-N share ·§: 77.0%share of the period's disclosed value held in the top-N positions; denominator is reported 13F value, not total assets · HHI (bps) ·§: 372integer Herfindahl–Hirschman index in basis points over disclosed position values · QoQ moves: 100

Filing history

AVAILABLE QUARTERS
Available filing periods
PeriodSource
2026-03-31EDGAR ↗

PLANNED sector rotation · Congress overlap · signals for this filer

Complete source filings on SEC EDGAR

The complete filing on EDGAR.

The position list above is served from the published Public Filings build — every position this filer reported for the selected quarter, as it reported it. This block is provenance, not a substitute: the filing itself is the record, and it is one click away. Serving this list is M2-CONTRACT §3, amended 2026-08-02; §3.1 keeps live EDGAR for filings newer than this build.

Open RTW INVESTMENTS, LP's 13F filings on SEC EDGAR ↗
Notes on this data

Quarter-end holdings as filed

Explore the full published position list and its source filing. This record excludes the manager’s cash, shorts and non-13(f) assets.

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Position changes retain the producer’s classification and comparability flags. Share counts and reported values describe different changes.

A snapshot, not current holdings

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Prior quarter not yet availableThis build carries one quarter for this manager: 2026-03-31. Notable managers carry four published quarters, others two.

Reported positions — 2026-03-31

1–87 of 87 issuers · $10.0B disclosed value over 88 rows · 0 undisclosed-value rows
Every row below carries ticker not yet mapped — stated once here rather than repeated on every row.
Positions RTW INVESTMENTS, LP reported for the quarter ended 2026-03-31, as that filer reported them
KindClassification is not joined into this reported-position view. Use the changed-positions view to compare the two published quarters.TickerThis list carries reported issuer names and security identities, without a dated ticker mapping. Symbols are not inferred from names.Issuera position composed from a base filing plus NEW-HOLDINGS amendments keeps every source row here; the composition's latest filed date is the one shown served from this build's published holdings (derived from the filer's own reported rows); every row resolves to its filingWeightShare of total reported value, calculated only when the full position list has disclosed values. This is 13F long value, not total assets.Valuevalue undisclosed on the filing: retained and counted, excluded from sums, never shown as $0SharesPosition changeShare change is available in the separate comparison view; it is not joined into this position list.WtCongressThe congressional transaction join is unavailable in this build.
MDGLverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)MADRIGAL PHARMACEUTICALS INC MADRIGAL PHARMACEUTICALS INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$1.0B1,993,68710.4%
INSMverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)INSMED INC INSMED INC · COM PAR $.01 CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$792M4,842,8807.9%
PTGXverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)PROTAGONIST THERAPEUTICS INC PROTAGONIST THERAPEUTICS INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$533M5,059,0535.3%
PTCTverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)PTC THERAPEUTICS INC PTC THERAPEUTICS INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$528M7,746,4155.3%
ARGXverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)ARGENX SE ARGENX SE · SPONSORED ADR CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$518M709,4465.2%
CGONverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)CG ONCOLOGY INC CG ONCOLOGY INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$473M6,984,8084.7%
CELCverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)CELCUITY INC CELCUITY INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$347M3,039,6213.5%
TNGXverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)TANGO THERAPEUTICS INC TANGO THERAPEUTICS INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$278M13,300,6202.8%
ERASverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)ERASCA INC ERASCA INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$261M16,157,1752.6%
NTRAverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)NATERA INC NATERA INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$250M1,250,0002.5%
RDNTverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)RADNET INC RADNET INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$239M4,285,0002.4%
TARSverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)TARSUS PHARMACEUTICALS INC TARSUS PHARMACEUTICALS INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$235M3,346,0252.3%
APGEverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)APOGEE THERAPEUTICS INC APOGEE THERAPEUTICS INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$234M2,782,0972.3%
SYREverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)SPYRE THERAPEUTICS INC SPYRE THERAPEUTICS INC · COM NEW CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$210M4,171,9962.1%
COGTverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)COGENT BIOSCIENCES INC COGENT BIOSCIENCES INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$210M5,458,6752.1%
IRTCverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)IRHYTHM HOLDINGS INC IRHYTHM HOLDINGS INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$197M1,668,5002.0%
STOKE THERAPEUTICS INC STOKE THERAPEUTICS INC · COM CUSIP 86150R107
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$183M5,623,5251.8%
CYTKverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)CYTOKINETICS INC CYTOKINETICS INC · COM NEW CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$179M2,721,1581.8%
ACADverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)ACADIA PHARMACEUTICALS INC ACADIA PHARMACEUTICALS INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$159M7,144,5241.6%
ESTABLISHMENT LABS HLDGS INC ESTABLISHMENT LABS HLDGS INC · COM CUSIP G31249108
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$151M2,655,6951.5%
APELLIS PHARMACEUTICALS INC APELLIS PHARMACEUTICALS INC · COM CUSIP 03753U106
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$148M3,685,0451.5%
IMCRverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)IMMUNOCORE HLDGS PLC IMMUNOCORE HLDGS PLC · ADS CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$147M4,869,7981.5%
RGENverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)REPLIGEN CORP REPLIGEN CORP · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$142M1,206,0001.4%
NBIXverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)NEUROCRINE BIOSCIENCES INC NEUROCRINE BIOSCIENCES INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$140M1,062,0721.4%
GHverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)GUARDANT HEALTH INC GUARDANT HEALTH INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$137M1,481,0331.4%
IMMATICS N.V IMMATICS N.V · SHS CUSIP N44445109
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$127M12,869,3401.3%
ZAI LAB LTD ZAI LAB LTD · ADR CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$124M6,574,0321.2%
BELITE BIO INC BELITE BIO INC · SPONSORED ADS CUSIP 07782B104
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$114M715,3321.1%
ISRGverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)INTUITIVE SURGICAL INC INTUITIVE SURGICAL INC · COM NEW CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$101M220,0001.0%
ORKAverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)ORUKA THERAPEUTICS INC ORUKA THERAPEUTICS INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$101M2,058,1481.0%
GH RESEARCH PLC GH RESEARCH PLC · ORDINARY SHARES CUSIP G3855L106
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$83.4M5,933,8150.8%
XENCOR INC XENCOR INC · COM CUSIP 98401F105
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$81.7M6,777,4610.8%
UROGEN PHARMA LTD UROGEN PHARMA LTD · COM CUSIP M96088105
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$81.7M4,543,8950.8%
CENTESSA PHARMACEUTICALS PLC CENTESSA PHARMACEUTICALS PLC · SPONSORED ADS CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$81.6M2,054,1750.8%
IMMUNOVANT INC IMMUNOVANT INC · COM CUSIP 45258J102
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$78.9M3,177,8490.8%
RAREverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)ULTRAGENYX PHARMACEUTICAL IN ULTRAGENYX PHARMACEUTICAL IN · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$76.4M3,648,7950.8%
HINGE HEALTH INC HINGE HEALTH INC · CL A CUSIP 433313103
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$74.4M1,930,0000.7%
CASTLE BIOSCIENCES INC CASTLE BIOSCIENCES INC · COM CUSIP 14843C105
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$67.7M2,758,3350.7%
ROCKET PHARMACEUTICALS INC
2 positions · 2 reported rows
Rows RTW INVESTMENTS, LP reported for ROCKET PHARMACEUTICALS INC, as it reported them
ROCKET PHARMACEUTICALS INC · COM CUSIP 77313F106 $63.3M17,687,772
ROCKET PHARMACEUTICALS INC · *W EXP 09/02/202 CUSIP 77313F114 $7.2K350,000
$63.3M18,037,7720.6%
TSHAverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)TAYSHA GENE THERAPIES INC TAYSHA GENE THERAPIES INC · COM SHS CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$61.2M13,680,2480.6%
ALKSverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)ALKERMES PLC ALKERMES PLC · SHS CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$59.1M1,672,3560.6%
COMPASS PATHWAYS PLC COMPASS PATHWAYS PLC · SPONSORED ADS CUSIP 20451W101
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$58.8M10,632,3900.6%
KODIAK SCIENCES INC KODIAK SCIENCES INC · COM CUSIP 50015M109
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$56.7M1,487,9340.6%
REPLverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)REPLIMUNE GROUP INC REPLIMUNE GROUP INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$56.3M7,356,9160.6%
CRNXverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)CRINETICS PHARMACEUTICALS IN CRINETICS PHARMACEUTICALS IN · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$52.7M1,451,3260.5%
QUREverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)UNIQURE NV UNIQURE NV · SHS CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$42.3M2,586,3560.4%
WAYverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)WAYSTAR HLDG CORP WAYSTAR HLDG CORP · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$39.3M1,630,0000.4%
ARWRverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)ARROWHEAD PHARMACEUTICALS IN ARROWHEAD PHARMACEUTICALS IN · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$36.7M585,6820.4%
ORCHESTRA BIOMED HLDGS INC ORCHESTRA BIOMED HLDGS INC · COM CUSIP 68572M106
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$35.3M8,306,0630.4%
VERASTEM INC VERASTEM INC · COM NEW CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$34.9M6,576,3060.3%
EVOMMUNE INC EVOMMUNE INC · COM SHS CUSIP 30054Y107
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$34.5M1,502,2350.3%
SYKverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)STRYKER CORPORATION STRYKER CORPORATION · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$32.9M100,0000.3%
SAVARA INC SAVARA INC · COM CUSIP 805111101
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$32.5M5,952,3800.3%
CANDEL THERAPEUTICS INC CANDEL THERAPEUTICS INC · COM CUSIP 137404109
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$31.5M6,422,0180.3%
AQUESTIVE THERAPEUTICS INC AQUESTIVE THERAPEUTICS INC · COM CUSIP 03843E104
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$30.8M7,426,4710.3%
AKTSverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)AKTIS ONCOLOGY INC AKTIS ONCOLOGY INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$28.5M1,592,0430.3%
NEUROGENE INC NEUROGENE INC · COM CUSIP 64135M105
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$27.5M1,362,4560.3%
CGEMverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)CULLINAN THERAPEUTICS INC CULLINAN THERAPEUTICS INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$24.2M1,705,9600.2%
COMPASS THERAPEUTICS INC COMPASS THERAPEUTICS INC · COM CUSIP 20454B104
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$22.1M4,186,5990.2%
DNTHverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)DIANTHUS THERAPEUTICS INC DIANTHUS THERAPEUTICS INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$20.8M248,0630.2%
FLGTverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)FULGENT GENETICS INC FULGENT GENETICS INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$20.5M1,289,0000.2%
BETA BIONICS INC BETA BIONICS INC · COM CUSIP 08659B102
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$20.0M2,000,0000.2%
KYMRverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)KYMERA THERAPEUTICS INC KYMERA THERAPEUTICS INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$20.0M240,0000.2%
CENTURY THERAPEUTICS INC CENTURY THERAPEUTICS INC · COM CUSIP 15673T100
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$19.7M8,695,6520.2%
BEAM THERAPEUTICS INC BEAM THERAPEUTICS INC · COM CUSIP 07373V105
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$13.6M570,3940.1%
AVALO THERAPEUTICS INC AVALO THERAPEUTICS INC · COM NEW CUSIP 05338F306
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$12.8M856,9620.1%
OCUGEN INC OCUGEN INC · COM CUSIP 67577C105
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$12.1M6,666,6660.1%
HEARTFLOW INC HEARTFLOW INC · COM CUSIP 42238D107
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$12.0M495,0000.1%
WVEverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)WAVE LIFE SCIENCES LTD WAVE LIFE SCIENCES LTD · SHS CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$9.8M1,350,0000.1%
PCSCverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)PERCEPTIVE CAP SOLUTIONS COR PERCEPTIVE CAP SOLUTIONS COR · CL A ORD SHS CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$8.1M742,5000.1%
JADE BIOSCIENCES INC JADE BIOSCIENCES INC · COM NEW CUSIP 008064206
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$8.1M573,2050.1%
CAPRICOR THERAPEUTICS INC CAPRICOR THERAPEUTICS INC · COM NEW CUSIP 14070B309
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$7.6M250,0000.1%
MILESTONE PHARMACEUTICALS IN MILESTONE PHARMACEUTICALS IN · COM CUSIP 59935V107
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$7.5M6,331,0010.1%
KALARIS THERAPEUTICS INC KALARIS THERAPEUTICS INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$7.5M1,300,0000.1%
INVENTIVA SA INVENTIVA SA · ADS CUSIP 46124U107
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$7.2M1,298,7020.1%
ATAIverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)ATAIBECKLEY INC ATAIBECKLEY INC · COM SHS CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$7.1M2,000,0000.1%
CBIOverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)CRESCENT BIOPHARMA INC. CRESCENT BIOPHARMA INC. · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$6.8M372,8560.1%
LARIMAR THERAPEUTICS INC LARIMAR THERAPEUTICS INC · COM CUSIP 517125100
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$6.8M1,500,0000.1%
TENAX THERAPEUTICS INC TENAX THERAPEUTICS INC · COM NEW CUSIP 88032L605
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$5.9M370,2460.1%
DFTXverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)DEFINIUM THERAPEUTICS INC DEFINIUM THERAPEUTICS INC · COM SHS CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$5.7M300,0000.1%
LUMEXA IMAGING HOLDINGS INC LUMEXA IMAGING HOLDINGS INC · COM CUSIP 550249106
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$5.6M650,0000.1%
4D MOLECULAR THERAPEUTICS IN 4D MOLECULAR THERAPEUTICS IN · COM CUSIP 35104E100
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$4.4M475,7370.0%
MDLNverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)MEDLINE INC MEDLINE INC · COM CL A CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$3.1M70,0000.0%
OMADA HEALTH INC OMADA HEALTH INC · COM CUSIP 68170A108
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$2.5M200,0000.0%
IRONverified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)DISC MEDICINE INC DISC MEDICINE INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$1.9M30,0000.0%
IMAGENEBIO INC IMAGENEBIO INC · COM CUSIP 45175G207
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$1.7M334,4450.0%
EXAGEN INC EXAGEN INC · COM CUSIP 30068X103
quarter ended 2026-03-31 filed filed 2026-05-15 +45d
$1.2M395,2310.0%
1–87 of 87 issuers · page 1 of 1
every row this filer reported for the quarter, as it reported it — cross-filer de-duplication is applied to issuer totals elsewhere and never deletes a row here
A 13F is a quarterly, long-only snapshot filed up to 45 days late — not current holdings. what a 13F covers ↗

13F reports cover LONG positions in Section 13(f) securities (US exchange-traded equities plus reportable options, warrants, certain convertibles) held by managers with at least $100M in such securities — so managers below that threshold are absent entirely. No short positions, no cash, no non-13(f) assets — not a full portfolio, and not a census of institutional ownership.

Positions are quarter-end snapshots filed up to 45 days late — not current holdings. A position may have been changed or closed before you ever see it, and is older still by however long ago that quarter ended.

Values are the manager's stated market value at quarter-end in era-dependent units (whole dollars for form versions effective 2023-01-03 onward, thousands before), normalized here to whole dollars with unit_basis carried on every record.

Affiliated managers may report the same position (otherManager), so one position can appear under more than one filer.

Positions under confidential treatment may be omitted until a later amendment discloses them.

These are disclosures, not investment advice (ARCHITECTURE.md §5.2 / M2-CONTRACT §5).